Description

4-(3-Chloro-2-Fluorophenyl)-4,5,6,7-Tetrahydro-3H-Imidazo[4,5-C]Pyridine is a high-value, heterocyclic organic compound featuring a fused imidazopyridine core, serving as a critical advanced intermediate in modern pharmaceutical research and development. Its molecular architecture, incorporating both chloro and fluoro substituents on the phenyl ring, makes it a versatile building block for constructing novel bioactive molecules, particularly in kinase inhibitor programs. This compound is essential for medicinal chemists and R&D teams in the pharmaceutical and biotechnology sectors focused on developing new therapeutic agents.

Application

This specialized chemical intermediate is designed for sophisticated synthetic applications, primarily within life sciences research and development.

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for targeted therapies.
• Kinase Inhibitor Development: Central to the research and synthesis of novel small-molecule inhibitors for various kinase targets implicated in diseases like cancer.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Bioconjugation & Probe Synthesis: Can be utilized to create chemical probes for biological target identification and validation studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Employed in university and institutional labs for cutting-edge chemical biology and drug discovery projects.

Basic Information

Product Name	4-(3-Chloro-2-Fluorophenyl)-4,5,6,7-Tetrahydro-3H-Imidazo[4,5-C]Pyridine
CAS No.	1189749-62-9
Molecular Formula	C12H11ClFN3
Molecular Weight	251.69 g/mol
Synonyms	4-(3-Chloro-2-fluorophenyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine; 4-(3-Chloro-2-fluorophenyl)-1,4,5,6,7,8-hexahydroimidazo[4,5-c]pyridine; 3H-Imidazo[4,5-c]pyridine, 4-(3-chloro-2-fluorophenyl)-4,5,6,7-tetrahydro-; 1189749-62-9; 4-(3-Chloro-2-fluorophenyl)-4,5,6,7-tetrahydroimidazo[4,5-c]pyridine
EINECS	Contact for details

Quality Control

Our 4-(3-Chloro-2-Fluorophenyl)-4,5,6,7-Tetrahydro-3H-Imidazo[4,5-C]Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, critical for sensitive R&D applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC, NMR, and MS. We adhere to cGMP guidelines where applicable to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). The compound is light-sensitive (store away from light). Keep container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.