Description

2-{[4-(1H-1,2,4-Triazol-1-Ylmethyl)Phenyl]Amino}-1,3-Thiazole-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular architecture combining triazole and thiazole carboxylic acid moieties. This compound is critical for research and development in medicinal chemistry, offering a versatile scaffold for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing next-generation therapeutics, particularly in areas requiring targeted molecular modifications.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Employed in the research and synthesis of novel crop protection agents and fungicides due to its heterocyclic structure.
• Bioconjugation & Probe Synthesis: The carboxylic acid functional group allows for conjugation to other molecules, useful in creating biochemical probes and diagnostic agents.
• Material Science Precursor: Investigated for the development of specialty polymers and organic electronic materials with specific functional properties.

Basic Information

Product Name	2-{[4-(1H-1,2,4-Triazol-1-Ylmethyl)Phenyl]Amino}-1,3-Thiazole-4-Carboxylic Acid
CAS No.	1189749-59-4
Molecular Formula	C13H11N5O2S
Molecular Weight	301.32 g/mol
Synonyms	2-((4-(1H-1,2,4-Triazol-1-ylmethyl)phenyl)amino)-1,3-thiazole-4-carboxylic acid; 2-{[4-(1H-1,2,4-Triazol-1-ylmethyl)phenyl]amino}-1,3-thiazole-4-carboxylic acid; 2-[(4-[(1H-1,2,4-Triazol-1-yl)methyl]phenyl)amino]-1,3-thiazole-4-carboxylic acid; 1189749-59-4; Thiazole-4-carboxylic acid, 2-[[4-[(1H-1,2,4-triazol-1-yl)methyl]phenyl]amino]-; AKOS025247193; AS-76379; ZINC000103486557
EINECS	Contact for details

Quality Control

Our 2-{[4-(1H-1,2,4-Triazol-1-Ylmethyl)Phenyl]Amino}-1,3-Thiazole-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its chemical nature, keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.