Description

Ethyl (2-Azidoethoxy-D4)Acetoacetate is a deuterated, azide-functionalized derivative of ethyl acetoacetate, serving as a specialized synthetic intermediate. This compound matters for its role in advanced organic synthesis, particularly in click chemistry and the preparation of isotopically labeled compounds for research and development. It is primarily needed by pharmaceutical researchers, agrochemical developers, and academic institutions engaged in medicinal chemistry, tracer studies, and materials science.

Application

• Key intermediate in the synthesis of deuterium-labeled active pharmaceutical ingredients (APIs) for pharmacokinetic and metabolic studies.
• Building block for click chemistry applications, facilitating the efficient construction of complex molecules via azide-alkyne cycloaddition.
• Precursor in the development of novel agrochemicals and specialty fine chemicals requiring specific isotopic labeling.
• Research reagent for studying reaction mechanisms and pathways using isotopic tracing techniques.
• Component in the synthesis of functionalized polymers and advanced materials with tailored properties.

Basic Information

Product Name	Ethyl (2-Azidoethoxy-D4)Acetoacetate
CAS No.	1189691-91-5
Molecular Formula	C8H9D4N3O4
Molecular Weight	215.21 g/mol (for deuterated form)
Synonyms	Ethyl 2-(2-Azidoethoxy-d4)acetoacetate; Ethyl (2-Azidoethoxy-1,1,2,2-d4)acetoacetate; Acetoacetic Acid (2-Azidoethoxy-d4) Ethyl Ester; 2-Azidoethoxy-d4 Acetoacetic Acid Ethyl Ester; Deuterated Ethyl Azidoethoxyacetoacetate; Ethyl 3-Oxo-4-(2-azidoethoxy-d4)butanoate
EINECS	Contact for details

Quality Control

Our Ethyl (2-Azidoethoxy-D4)Acetoacetate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ¹³C) and HPLC analysis, to confirm identity, chemical purity, and isotopic enrichment. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.