Description

3-Bromo-5-Chloropyridine-2-Carboxylic Acid is a high-value halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a carboxylic acid and halogen substituents, makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides with specific modes of action.
• Ligand and Catalyst Development: Used to create sophisticated chelating ligands for metal catalysts in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Intermediate for synthesizing functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes and tags used in biochemical and diagnostic research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research organizations for custom synthesis projects and process development.

Basic Information

Product Name	3-Bromo-5-Chloropyridine-2-Carboxylic Acid
CAS No.	1189513-50-5
Molecular Formula	C6H3BrClNO2
Molecular Weight	236.45 g/mol
Synonyms	2-Carboxy-3-bromo-5-chloropyridine; 5-Chloro-3-bromopicolinic acid; 3-Bromo-5-chloropicolinic acid; 3-Bromo-5-chloro-2-pyridinecarboxylic acid; 2-Pyridinecarboxylic acid, 3-bromo-5-chloro-; Picolinic acid, 3-bromo-5-chloro-; (3-Bromo-5-chloropyridin-2-yl)methanol (oxidized form)
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Chloropyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements of our global clientele. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.