Description

1-[4-(1,1-Difluoroethyl)Phenyl]-Ethanone is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity and electronic properties imparted by the difluoroethyl group, enabling precise molecular modifications. This high-purity intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors or CNS-active molecules.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in display and lighting technologies.
• Advanced Polymer Modification: Incorporated as a monomer or cross-linking agent to develop specialty polymers with enhanced chemical resistance and thermal properties.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial labs to study novel fluorination reactions and catalytic processes.
• Fluorinated Surfactant & Coating Agent: Acts as a precursor for surface-active agents and coatings that require low surface energy and high stability.

Basic Information

Product Name	1-[4-(1,1-Difluoroethyl)Phenyl]-Ethanone
CAS No.	1188932-40-2
Molecular Formula	C10H10F2O
Molecular Weight	184.18 g/mol
Synonyms	4'-(1,1-Difluoroethyl)acetophenone; 1-[4-(1,1-Difluoroethyl)phenyl]ethan-1-one; 4-Acetyl-α,α-difluoroethylbenzene; p-(1,1-Difluoroethyl)acetophenone; DFEA; 4-(1,1-Difluoroethyl)acetophenone; 1-(4-(1,1-Difluoroethyl)phenyl)ethanone
EINECS	Contact for details

Quality Control

Our 1-[4-(1,1-Difluoroethyl)Phenyl]-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee batch-to-batch consistency and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. The container should be kept tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.