Description

2-Bromo-5-Chloro-4-(Trifluoromethyl)Pyridine is a high-value, multi-functional halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine, chlorine, and trifluoromethyl substituents, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Precursor: Employed in the synthesis of functionalized ligands for catalysis and advanced organic electronic materials.
• Cross-Coupling Reactions: Serves as a versatile substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl systems.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry teams exploring new chemical entities and optimizing synthetic routes.

Basic Information

Product Name	2-Bromo-5-Chloro-4-(Trifluoromethyl)Pyridine
CAS No.	1188476-72-3
Molecular Formula	C6H2BrClF3N
Molecular Weight	260.44 g/mol
Synonyms	2-Bromo-5-chloro-4-(trifluoromethyl)pyridine; 4-(Trifluoromethyl)-2-bromo-5-chloropyridine; 5-Chloro-2-bromo-4-(trifluoromethyl)pyridine; 2-Bromo-5-chloro-4-trifluoromethylpyridine; Pyridine, 2-bromo-5-chloro-4-(trifluoromethyl)-; 1188476-72-3
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-Chloro-4-(Trifluoromethyl)Pyridine is manufactured and tested under a strict quality management system. We guarantee high-purity material suitable for demanding research and scale-up applications. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.