Description

9-Chloro-2,3,4,6,7,11B-Hexahydro-1H-Pyrazino[2,1-A]Isoquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant commercial interest for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in the development of novel therapeutic agents, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step production of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• Process Chemistry Development: Used in route scouting, optimization, and scale-up activities for new chemical entities (NCEs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studies in organic synthesis methodology and heterocyclic chemistry.

Basic Information

Product Name	9-Chloro-2,3,4,6,7,11B-Hexahydro-1H-Pyrazino[2,1-A]Isoquinoline
CAS No.	1188331-36-3
Molecular Formula	C12H15ClN2
Molecular Weight	222.71 g/mol
Synonyms	9-Chloro-1,2,3,4,6,7-hexahydro-11bH-pyrazino[2,1-a]isoquinoline; 9-Chloro-2,3,4,6,7,11b-hexahydro-1H-pyrazino[2,1-a]isoquinoline; 9-Chloro-1H,2H,3H,4H,6H,7H,11bH-pyrazino[2,1-a]isoquinoline; 9-Chlorohexahydropyrazinoisoquinoline; 1188331-36-3; 9-Chloro-1,2,3,4,6,7-hexahydro-11bH-pyrazino[2,1-a]isoquinoline
EINECS	Contact for details

Quality Control

Our 9-Chloro-2,3,4,6,7,11B-Hexahydro-1H-Pyrazino[2,1-A]Isoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) detailing comprehensive test results, including assay and impurity profiles, are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.