Description

tert-Butyl 3-Methoxy-4-Oxopiperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine scaffold with protected amine and ketone functionalities. This compound is of significant value for its role as a versatile building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing novel drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of central nervous system (CNS) and other therapeutic agents.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Used in the scale-up and optimization of synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Custom Synthesis: A starting material for the contract manufacturing of specialized fine chemicals and bespoke molecular entities.
• Protease Inhibitor Synthesis: Potential building block in the synthesis of compounds targeting various protease enzymes.
• Academic Research: Employed in university and institutional labs for methodological development and novel heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	tert-Butyl 3-Methoxy-4-Oxopiperidine-1-Carboxylate
CAS No.	1188265-31-7
Molecular Formula	C11H19NO4
Molecular Weight	229.27 g/mol
Synonyms	1-Boc-3-methoxy-4-oxopiperidine; 1-(tert-Butoxycarbonyl)-3-methoxy-4-piperidinone; 3-Methoxy-4-oxo-1-piperidinecarboxylic acid tert-butyl ester; tert-Butyl 3-methoxy-4-oxo-1-piperidinecarboxylate; 4-Oxo-3-methoxypiperidine-1-carboxylic acid tert-butyl ester; 1-Boc-3-methoxy-4-piperidinone; Boc-3-methoxy-4-oxopiperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Methoxy-4-Oxopiperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.