Description

Ethyl 3-(Pyridin-4-Ylmethyl)Piperidine-3-Carboxylate 2Hcl is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core substituted with a pyridinylmethyl group. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for synthesizing novel bioactive molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for neurological and psychiatric targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component in the development of potential APIs for various therapeutic areas.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs) serving the pharmaceutical industry.

Basic Information

Item	Details
Product Name	Ethyl 3-(Pyridin-4-Ylmethyl)Piperidine-3-Carboxylate 2Hcl
CAS No.	1188263-73-1
Molecular Formula	C15H22N2O2 · 2HCl
Molecular Weight	343.27 g/mol (Free base: 262.35 g/mol)
Synonyms	Ethyl 3-[(4-Pyridinyl)methyl]-3-piperidinecarboxylate dihydrochloride; 3-(Pyridin-4-ylmethyl)piperidine-3-carboxylic acid ethyl ester dihydrochloride; 1,1'-Methylenebis[3-piperidinecarboxylic acid ethyl ester] dihydrochloride (related); 4-Pyridinemethanamine, N-(3-carbethoxy-3-piperidyl)-, dihydrochloride; Ethyl 3-(4-Pyridylmethyl)piperidine-3-carboxylate 2HCl; CAS 1188263-73-1
EINECS	Contact for details

Quality Control

Our Ethyl 3-(Pyridin-4-Ylmethyl)Piperidine-3-Carboxylate 2Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and desiccated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.