Description

Ethyl 3-(Pyridin-3-Ylmethyl)Piperidine-3-Carboxylate 2Hcl is a high-purity, advanced pharmaceutical intermediate with the CAS number 1188263-63-9. This compound is of significant value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, particularly in central nervous system (CNS) and oncology research.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing piperidine and pyridine-containing molecular scaffolds with specific stereochemistry.
• Research & Development (R&D): Essential for academic and industrial labs exploring new chemical entities and structure-activity relationships (SAR).
• Process Chemistry: Serves as a standardized starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of clinical trial materials.

Basic Information

Product Name	Ethyl 3-(Pyridin-3-Ylmethyl)Piperidine-3-Carboxylate 2Hcl
CAS No.	1188263-63-9
Molecular Formula	C15H22N2O2 · 2HCl
Molecular Weight	351.27 g/mol (Free base: 262.35 g/mol)
Synonyms	Ethyl 3-[(pyridin-3-yl)methyl]piperidine-3-carboxylate dihydrochloride; 3-Pyridinemethanol, α-(3-carboxy-3-piperidinyl)-, ethyl ester, dihydrochloride; Ethyl 3-(3-pyridylmethyl)-3-piperidinecarboxylate dihydrochloride; 1188263-63-9; UNII-9F8Z8U6Q0F; 9F8Z8U6Q0F; SCHEMBL23346831; AKOS040759626
EINECS	Contact for details

Quality Control

Our Ethyl 3-(Pyridin-3-Ylmethyl)Piperidine-3-Carboxylate 2Hcl is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical R&D. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, residual solvent analysis, and identification by spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0% (Total impurities ≤ 1.0%)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.