Description

1-(Pyridin-3-Yl)Cyclopropanamine (Hydrochloride) is a high-purity, advanced pharmaceutical intermediate and versatile organic building block. This compound is valued for its unique cyclopropane-pyridine hybrid structure, which is critical for modulating biological activity and physicochemical properties in drug discovery. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other disease areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery projects.
• Ligand Synthesis: Serves as a precursor for creating novel ligands in catalysis and receptor-binding studies.
• Chemical Biology Probes: Incorporated into molecular probes for studying biological pathways and enzyme functions.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.
• Academic & Industrial R&D: Employed in organic synthesis for constructing complex molecules with cyclopropane motifs.

Basic Information

Product Name	1-(Pyridin-3-Yl)Cyclopropanamine (Hydrochloride)
CAS No.	1187932-50-8
Molecular Formula	C8H11N2 • HCl
Molecular Weight	170.65 g/mol (free base: 134.19 g/mol)
Synonyms	1-(3-Pyridinyl)cyclopropanamine hydrochloride; 1-(Pyridin-3-yl)cyclopropan-1-amine hydrochloride; 3-(1-Aminocyclopropyl)pyridine hydrochloride; 1-(3-Pyridyl)cyclopropylamine HCl; 1-Amino-1-(3-pyridyl)cyclopropane hydrochloride; 3-Cyclopropylaminopyridine hydrochloride; 1-(Pyridin-3-yl)cyclopropanamine HCl; 1-(3-Pyridinyl)-1-cyclopropanamine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(Pyridin-3-Yl)Cyclopropanamine (Hydrochloride) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if opened for prolonged use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.