Description

Imidazo[1,5-A]Pyridin-1-Ylmethanamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 1187932-15-5. This compound is a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for therapeutic agents targeting the central nervous system. It is essential for research and development chemists, process development scientists, and manufacturers in the pharmaceutical and biotechnology sectors who require reliable, high-quality intermediates for complex synthetic routes.

Application

This specialized intermediate serves as a key precursor in several high-value chemical synthesis pathways. Its primary applications include:

• Pharmaceutical Intermediate: Core building block for the synthesis of novel drug candidates, especially in neurological and psychiatric disorder research.
• Organic Synthesis Reagent: Used in the construction of complex heterocyclic frameworks common in medicinal chemistry.
• Research & Development: Critical material for academic and industrial R&D labs exploring new chemical entities and structure-activity relationships.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for potential commercial APIs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	Imidazo[1,5-A]Pyridin-1-Ylmethanamine Hydrochloride
CAS No.	1187932-15-5
Molecular Formula	C9H10N3·HCl
Molecular Weight	197.66 g/mol (Free base: 160.20 g/mol)
Synonyms	1-(Aminomethyl)imidazo[1,5-a]pyridine hydrochloride; Imidazo[1,5-a]pyridin-1-ylmethanamine HCl; 1-(Imidazo[1,5-a]pyridin-1-yl)methanamine hydrochloride; 1-(Aminomethyl)-1H-imidazo[1,5-a]pyridine hydrochloride; (Imidazo[1,5-a]pyridin-1-ylmethyl)amine hydrochloride
EINECS	Contact for details

Quality Control

Our production of Imidazo[1,5-A]Pyridin-1-Ylmethanamine Hydrochloride adheres to stringent quality management protocols. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific client or regulatory requirements. We support cGMP-compliant manufacturing for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere to prevent degradation and ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.