Description

5,6,7,8-Tetrahydro-[1,8]Naphthyridine-2-Carboxylic Acid Hydrochloride is a high-purity, heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of chemical probes and enzyme inhibitors for biological research.
• Material Science: Acts as a monomer or functional additive in the synthesis of advanced polymers and organic electronic materials.
• Academic & Contract Research: Serves as a standard or starting material in university laboratories and CROs (Contract Research Organizations) for method development and novel synthetic route exploration.

Basic Information

Product Name	5,6,7,8-Tetrahydro-[1,8]Naphthyridine-2-Carboxylic Acid Hydrochloride
CAS No.	1187931-99-2
Molecular Formula	C9H11ClN2O2
Molecular Weight	214.65 g/mol
Synonyms	5,6,7,8-Tetrahydro-1,8-naphthyridine-2-carboxylic acid hydrochloride; 2-Carboxy-5,6,7,8-tetrahydro-1,8-naphthyridine hydrochloride; THNCA-HCl; 1,8-Naphthyridine-2-carboxylic acid, 5,6,7,8-tetrahydro-, hydrochloride; 1187931-99-2
EINECS	Contact for details

Quality Control

Our production of 5,6,7,8-Tetrahydro-[1,8]Naphthyridine-2-Carboxylic Acid Hydrochloride adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical applications. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support development and commercial projects with material produced under a quality management system and can provide custom synthesis to meet specific pharmacopeial (e.g., USP) or internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.