Description

Benzyl (+/-)-trans-4-Methyl-Piperidine-2-Carboxylate Hydrochloride is a high-purity chiral piperidine derivative, a crucial building block in modern organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with defined stereochemistry. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, especially those targeting neurological pathways.
• Chemical Synthesis Building Block: Used in the construction of complex piperidine-containing frameworks for medicinal chemistry and process research.
• Asymmetric Synthesis: Serves as a precursor for chiral ligands, catalysts, or auxiliaries used in stereoselective transformations.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the synthesis of biologically active compounds.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents with specific activity profiles.

Basic Information

Item	Details
Product Name	Benzyl (+/-)-trans-4-Methyl-Piperidine-2-Carboxylate Hydrochloride
CAS No.	1187927-11-2
Molecular Formula	C15H22ClNO2
Molecular Weight	283.79 g/mol
Synonyms	Benzyl trans-4-Methylpipecolate Hydrochloride; (±)-Benzyl trans-4-Methylpipecolate Hydrochloride; Benzyl 4-Methyl-2-piperidinecarboxylate Hydrochloride (racemic trans); trans-4-Methyl-DL-pipecolic Acid Benzyl Ester Hydrochloride; 4-Methylpipecolic Acid Benzyl Ester Hydrochloride (trans, racemic); Benzyl 4-Methyl-2-piperidinecarboxylate HCl; (rac)-Benzyl trans-4-methylpipecolate hydrochloride
EINECS	Contact for details

Quality Control

Our Benzyl (+/-)-trans-4-Methyl-Piperidine-2-Carboxylate Hydrochloride is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99:1 trans/cis ratio
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.