Description

3-[2-4-Pyridinyl)Acetyl]-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a piperidine scaffold with a pyridinylacetyl substituent. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing therapeutics targeting the central nervous system and other disease areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological receptors.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic molecules.
• API Development: Serves as a precursor in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Utilized in the development of probes for studying enzyme function and biological pathways.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic projects.
• Academic Research: Used in university and institutional labs for exploratory organic synthesis and pharmacological studies.

Basic Information

Product Name	3-[2-4-Pyridinyl)Acetyl]-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1187927-03-2
Molecular Formula	C17H24N2O3
Molecular Weight	304.39 g/mol
Synonyms	tert-Butyl 3-(2-(pyridin-4-yl)acetyl)piperidine-1-carboxylate; 1-Boc-3-(2-(4-pyridyl)acetyl)piperidine; 1-(tert-Butoxycarbonyl)-3-[(pyridin-4-yl)acetyl]piperidine; 3-(2-(4-Pyridyl)acetyl)piperidine-1-carboxylic acid tert-butyl ester; 4-Pyridineacetic acid, 1-(1,1-dimethylethoxycarbonyl)-3-piperidinyl ester; BOC-Piperidine-3-(4-Pyridylacetyl)
EINECS	Contact for details

Quality Control

Our 3-[2-4-Pyridinyl)Acetyl]-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring suitability for demanding pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.