Description

2-(4-Carboxypiperidin-1-Yl)Nicotinic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct molecular structure combining nicotinic and piperidine carboxylic acid moieties. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for targeted therapies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological and metabolic disorders.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new chemical entities.
• API Synthesis: Serves as a crucial building block in the multi-step manufacturing process of final active pharmaceutical ingredients.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.

Basic Information

Product Name	2-(4-Carboxypiperidin-1-Yl)Nicotinic Acid
CAS No.	1187568-83-7
Molecular Formula	C12H14N2O4
Molecular Weight	250.25 g/mol
Synonyms	1-(6-Carboxypyridin-2-yl)piperidine-4-carboxylic acid; 2-(4-Carboxypiperidin-1-yl)pyridine-6-carboxylic acid; Nicotinic acid, 2-(4-carboxy-1-piperidinyl)-; 2-Piperidin-4-ylcarbamoylnicotinic acid (related); 2-(4-Carboxypiperidino)nicotinic acid; 6-Carboxy-2-(4-carboxypiperidin-1-yl)pyridine
EINECS	Contact for details

Quality Control

Our 2-(4-Carboxypiperidin-1-Yl)Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.