Description

1H-Pyrrolo[2,3-B]Pyridine, 4-Bromo-2-Cyclopropyl-5-Fluoro- is a high-value, multi-functional heterocyclic building block essential for modern pharmaceutical and agrochemical research. Its unique molecular architecture, featuring a fused pyrrolopyridine core with bromo, fluoro, and cyclopropyl substituents, makes it a critical intermediate for constructing complex bioactive molecules. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors, antiviral agents, and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the halogenated pyrrolopyridine scaffold.
• Material Science Precursor: Serves as a specialized monomer or ligand in the synthesis of organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a molecular tag in probe development.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 4-Bromo-2-Cyclopropyl-5-Fluoro-
CAS No.	1187449-21-3
Molecular Formula	C10H8BrFN2
Molecular Weight	255.09 g/mol
Synonyms	4-Bromo-2-cyclopropyl-5-fluoro-1H-pyrrolo[2,3-b]pyridine; 4-Bromo-2-cyclopropyl-5-fluoro-7-azaindole; 5-Fluoro-4-bromo-2-cyclopropyl-1H-pyrrolo[2,3-b]pyridine; 2-Cyclopropyl-4-bromo-5-fluoro-1H-pyrrolo[2,3-b]pyridine; 4-Bromo-2-cyclopropyl-5-fluoro-7H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 4-bromo-2-cyclopropyl-5-fluoro-; 1187449-21-3
EINECS	Contact for details

Quality Control

Every batch of 1H-Pyrrolo[2,3-B]Pyridine, 4-Bromo-2-Cyclopropyl-5-Fluoro- is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are supplied with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.