Description

3-Bromo-2-(4-Propylpiperazino)-5-Picoline, Hcl is a high-purity, advanced pharmaceutical intermediate characterized by its specific piperazine-substituted picoline structure. This compound is critical for research and development in medicinal chemistry, serving as a key building block for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and receptor-targeted drugs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of potential drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold in the development of new APIs for preclinical and clinical studies.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme and receptor function.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Item	Detail
Product Name	3-Bromo-2-(4-Propylpiperazino)-5-Picoline, Hcl
CAS No.	1187386-03-3
Molecular Formula	C13H21BrClN3
Molecular Weight	334.68 g/mol
Synonyms	3-Bromo-2-(4-propylpiperazin-1-yl)-5-methylpyridine hydrochloride; 2-(4-Propylpiperazin-1-yl)-3-bromo-5-methylpyridine hydrochloride; 3-Bromo-2-(4-propyl-1-piperazinyl)-5-picoline hydrochloride; 5-Methyl-3-bromo-2-(4-propylpiperazino)pyridine HCl; 1187386-03-3; 3-Bromo-2-(4-propylpiperazino)-5-methylpyridine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-(4-Propylpiperazino)-5-Picoline, Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.