Description

1-(4-(5-Bromopyridin-2-Yl)Piperazin-1-Yl)-2,2,2-Trifluoroethanone is a high-purity, advanced pharmaceutical intermediate featuring a bromopyridine and trifluoroacetyl-piperazine scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules targeting central nervous system and oncological pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in kinase inhibitor and receptor modulator programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its versatile bromine handle for further functionalization.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study biological pathways and protein functions.
• Agrochemical Research: Potential intermediate in the development of advanced crop protection agents and pesticides.
• Material Science: Can be investigated as a monomer or precursor for specialty polymers and advanced materials with unique electronic properties.

Basic Information

Product Name	1-(4-(5-Bromopyridin-2-Yl)Piperazin-1-Yl)-2,2,2-Trifluoroethanone
CAS No.	1187385-94-9
Molecular Formula	C11H10BrF3N3O
Molecular Weight	337.12 g/mol
Synonyms	2,2,2-Trifluoro-1-[4-(5-bromo-2-pyridinyl)-1-piperazinyl]ethanone; 1-[4-(5-Bromopyridin-2-yl)piperazin-1-yl]-2,2,2-trifluoroethanone; 5-Bromo-2-(4-(trifluoroacetyl)piperazin-1-yl)pyridine; 2,2,2-Trifluoro-1-(4-(5-bromopyridin-2-yl)piperazin-1-yl)ethan-1-one; 1187385-94-9; 5-Bromo-2-(4-(2,2,2-trifluoroacetyl)piperazin-1-yl)pyridine
EINECS	Contact for details

Quality Control

Our 1-(4-(5-Bromopyridin-2-Yl)Piperazin-1-Yl)-2,2,2-Trifluoroethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.