Description

2-Chloro-5-(4-Cyanobenzoyl)Pyridine is a high-value, multi-functional heterocyclic building block used in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique molecular scaffold enables precise structural modifications. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating complex ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and functional polymers.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.
• Academic and Industrial R&D: A valuable reagent for method development and exploring new chemical reactions in laboratory settings.

Basic Information

Product Name	2-Chloro-5-(4-Cyanobenzoyl)Pyridine
CAS No.	1187171-36-3
Molecular Formula	C13H7ClN2O
Molecular Weight	242.66 g/mol
Synonyms	2-Chloro-5-(4-cyanobenzoyl)pyridine; 4-(6-Chloropyridin-3-yl)(oxo)methyl]benzonitrile; 2-Chloro-5-(4-cyanobenzoyl)pyridine; (4-Cyanophenyl)(6-chloro-3-pyridinyl)methanone; 6-Chloro-3-pyridinyl(4-cyanophenyl)methanone; 2-Chloro-5-(p-cyanobenzoyl)pyridine; 2-Chloro-5-(4-cyanobenzoyl)pyridine CAS 1187171-36-3
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(4-Cyanobenzoyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.