Description

2-(2-Bromobenzoyl)-6-Methylpyridine is a specialized brominated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a halogenated benzoyl group with a methyl-substituted pyridine ring, enabling precise chemical modifications. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in medicinal chemistry programs targeting novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates with pyridine-based pharmacophores.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides where the bromobenzoyl moiety acts as a crucial synthetic handle.
• Ligand Synthesis: Serves as a starting material for creating sophisticated chelating ligands in coordination chemistry and catalysis.
• Material Science: Employed in the research and development of organic electronic materials and advanced polymers.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination.
• Academic & Contract Research: A valuable reagent for methodological studies and library synthesis in academic and contract research organizations (CROs).

Basic Information

Product Name	2-(2-Bromobenzoyl)-6-Methylpyridine
CAS No.	1187169-94-3
Molecular Formula	C13H10BrNO
Molecular Weight	276.13 g/mol
Synonyms	2-(2-Bromobenzoyl)-6-picoline; 6-Methyl-2-(2-bromobenzoyl)pyridine; (2-Bromophenyl)(6-methylpyridin-2-yl)methanone; 2-(2-Bromobenzoyl)-6-methylpyridine; 2-Pyridinecarboxaldehyde, 6-methyl-, 2-bromophenylhydrazone (related); Methanone, (2-bromophenyl)(6-methyl-2-pyridinyl)-; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-(2-Bromobenzoyl)-6-Methylpyridine is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality system is designed to support cGMP and ISO-guided applications where documentation and traceability are paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.