Description

2-Chloro-5-(3,5-Difluorobenzoyl)Pyridine is a high-value, multi-functional heterocyclic building block of significant importance in modern synthetic chemistry. Its core value lies in its precise molecular architecture, which serves as a critical intermediate for the development of advanced active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in kinase inhibitor research and other small-molecule therapeutics.
• Agrochemical Synthesis: Used as a core building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Serves as a precursor for creating specialized ligands, organic electronic materials, and liquid crystals.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and process development projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2-Chloro-5-(3,5-Difluorobenzoyl)Pyridine
CAS No.	1187169-72-7
Molecular Formula	C12H6ClF2NO
Molecular Weight	253.63 g/mol
Synonyms	(3,5-Difluorophenyl)(6-chloropyridin-3-yl)methanone; 2-Chloro-5-(3,5-difluorobenzoyl)pyridine; 6-Chloro-3-(3,5-difluorobenzoyl)pyridine; 5-(3,5-Difluorobenzoyl)-2-chloropyridine; 2-Chloro-5-(3,5-difluorophenylcarbonyl)pyridine; CAS 1187169-72-7; Pyridine, 2-chloro-5-[(3,5-difluorophenyl)carbonyl]-; 1187169-72-7
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(3,5-Difluorobenzoyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and adherence to ISO standards ensure reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.