Description

2-Chloro-5-(3,4-Difluorobenzoyl)Pyridine is a high-value, multi-functional heterocyclic building block characterized by its pyridine core and halogenated benzoyl substituent. This compound is essential for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive scaffold.
• Material Science: Serves as a building block for creating advanced organic materials, such as ligands for catalysts or components in organic electronics.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a versatile electrophile or directing group in metal-catalyzed transformations.
• Academic & R&D: A valuable reagent for methodological development and exploring new chemical spaces in university and corporate research laboratories.

Basic Information

Product Name	2-Chloro-5-(3,4-Difluorobenzoyl)Pyridine
CAS No.	1187169-69-2
Molecular Formula	C12H6ClF2NO
Molecular Weight	253.63 g/mol
Synonyms	2-Chloro-5-(3,4-difluorobenzoyl)pyridine; (3,4-Difluorophenyl)(6-chloropyridin-3-yl)methanone; 6-Chloro-3-pyridinyl 3,4-difluorophenyl ketone; 5-(3,4-Difluorobenzoyl)-2-chloropyridine; 2-Chloro-5-(3,4-difluorobenzoyl)pyridine CAS 1187169-69-2
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(3,4-Difluorobenzoyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Custom synthesis and purification to meet specific research or cGMP standards are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.