Description

2-Chloro-5-(3-Nitrobenzoyl)Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyridine core functionalized with chloro and nitrobenzoyl groups. This compound matters as a critical building block in modern organic synthesis, enabling the development of novel active pharmaceutical ingredients (APIs) and agrochemicals with targeted properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecular entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its heterocyclic structure for bioactivity.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP guidelines.

Basic Information

Item	Detail
Product Name	2-Chloro-5-(3-Nitrobenzoyl)Pyridine
CAS No.	1187169-55-6
Molecular Formula	C12H7ClN2O3
Molecular Weight	262.65 g/mol
Synonyms	2-Chloro-5-(3-nitrobenzoyl)pyridine; 5-(3-Nitrobenzoyl)-2-chloropyridine; 2-Chloro-5-(3-nitrobenzoyl)pyridine; 2-Chloro-5-(3-nitrobenzoyl)pyridine; (3-Nitrobenzoyl)-2-chloro-5-pyridine; Pyridine, 2-chloro-5-(3-nitrobenzoyl)-; 1187169-55-6
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(3-Nitrobenzoyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with ICH guidelines, and we support development under cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled and stored away from direct light exposure to maintain stability.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.