Description

2-Methyl-4-(2-Trifluoromethylbenzoyl)Pyridine is a high-value, multi-functional organic intermediate characterized by its unique pyridine core substituted with a trifluoromethylbenzoyl group. This compound matters for its role as a critical building block in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its specific structure imparts desirable properties. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring fluorinated molecules for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoromethyl group can improve efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a sophisticated ligand precursor in organometallic chemistry for creating catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or fluorinated polymers, due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized as a core structure for designing fluorescent probes or enzyme inhibitors in biochemical research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Item	Details
Product Name	2-Methyl-4-(2-Trifluoromethylbenzoyl)Pyridine
CAS No.	1187168-80-4
Molecular Formula	C14H10F3NO
Molecular Weight	265.23 g/mol
Synonyms	2-Methyl-4-(2-(trifluoromethyl)benzoyl)pyridine; 4-(2-(Trifluoromethyl)benzoyl)-2-picoline; 2-Methyl-4-[(2-trifluoromethyl)benzoyl]pyridine; α-(2-Trifluoromethylphenyl)-2-methyl-4-pyridyl ketone; 2-Methyl-4-(α,α,α-trifluoro-o-toluoyl)pyridine; 4-(2-Trifluoromethylbenzoyl)-2-methylpyridine; 2-Picoline, 4-(2-(trifluoromethyl)benzoyl)-
EINECS	Contact for details

Quality Control

Our 2-Methyl-4-(2-Trifluoromethylbenzoyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.