Description

3-(2,5-Difluorobenzoyl)-4-Methylpyridine is a high-purity, advanced pharmaceutical intermediate characterized by its difluorobenzoyl and methylpyridine functional groups. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modification. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug molecules, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the difluoro moiety can enhance biological activity and environmental stability.
• Ligand and Catalyst Precursor: Serves as a precursor for synthesizing specialized ligands used in catalytic processes and material science.
• Chemical Synthesis Reference Standard: Employed as a high-purity standard in analytical chemistry for method development and quality control.
• Academic and R&D Laboratories: Utilized in university and corporate research settings for exploring new organic reactions and heterocyclic chemistry.
• Fluorinated Compound Library Synthesis: A valuable component for creating libraries of fluorinated compounds for high-throughput screening in drug discovery.

Basic Information

Product Name	3-(2,5-Difluorobenzoyl)-4-Methylpyridine
CAS No.	1187168-40-6
Molecular Formula	C13H9F2NO
Molecular Weight	233.21 g/mol
Synonyms	4-Methyl-3-(2,5-difluorobenzoyl)pyridine; 3-(2,5-Difluorobenzoyl)-4-picoline; (2,5-Difluorophenyl)(4-methylpyridin-3-yl)methanone; 4-Methyl-3-(2,5-difluorobenzoyl)pyridine; 3-(2,5-Difluorobenzoyl)-4-methylpyridine; 1187168-40-6; Methanone, (2,5-difluorophenyl)(4-methyl-3-pyridinyl)-
EINECS	Contact for details

Quality Control

Our 3-(2,5-Difluorobenzoyl)-4-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.