Description

5-(2,6-Dimethoxybenzoyl)-2-Methylpyridine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct dimethoxybenzoyl-substituted pyridine structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), where its specific molecular framework serves as a key building block. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Active Pharmaceutical Ingredient (API) Synthesis: Incorporated into the final chemical structure of target APIs, requiring stringent purity and quality control.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method validation in API production.

Basic Information

Item	Details
Product Name	5-(2,6-Dimethoxybenzoyl)-2-Methylpyridine
CAS No.	1187167-87-8
Molecular Formula	C₁₅H₁₅NO₃
Molecular Weight	257.29 g/mol
Synonyms	2-Methyl-5-(2,6-dimethoxybenzoyl)pyridine; 2,6-Dimethoxy-α-(2-methyl-5-pyridinyl)benzene methanol; 5-(2,6-Dimethoxybenzoyl)-2-picoline; 2-Picoline, 5-(2,6-dimethoxybenzoyl)-; (2-Methylpyridin-5-yl)(2,6-dimethoxyphenyl)methanone
EINECS	Contact for details

Quality Control

Our 5-(2,6-Dimethoxybenzoyl)-2-Methylpyridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with complete batch data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.