Description

4-(2-Fluorobenzoyl)-2-Methylpyridine is a high-purity fluorinated pyridine derivative, a key building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific fluorinated motifs into target molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and pesticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a sophisticated ligand precursor in organometallic chemistry and catalysis for asymmetric synthesis.
• Material Science Research: Employed in the creation of specialty polymers and organic electronic materials where fluorinated aromatic systems are required.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags and molecular probes for biological imaging and diagnostic applications.

Basic Information

Product Name	4-(2-Fluorobenzoyl)-2-Methylpyridine
CAS No.	1187167-17-4
Molecular Formula	C13H10FNO
Molecular Weight	215.22 g/mol
Synonyms	2-Methyl-4-(2-fluorobenzoyl)pyridine; 4-(2-Fluorobenzoyl)-2-picoline; 2-Fluoro-α-(2-methyl-4-pyridinyl)benzene methanol (keto form); (2-Fluorophenyl)(2-methylpyridin-4-yl)methanone; 2-Methyl-4-(2-fluorobenzoyl)pyridine; 4-(2-Fluorobenzoyl)-2-methylpyridine; 1187167-17-4
EINECS	Contact for details

Quality Control

Our 4-(2-Fluorobenzoyl)-2-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.