Description

2-(3,4-Difluorobenzoyl)-6-Methylpyridine is a high-purity, advanced pharmaceutical intermediate with the CAS number 1187166-19-3. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular architecture. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel small-molecule drugs, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new generation herbicides and pesticides with specific activity profiles.
• Material Science: Serves as a precursor for organic electronic materials and liquid crystals due to its conjugated system and fluorine atoms.
• Academic & Contract Research: Essential reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in academic and CRO settings.
• Fluorinated Compound Synthesis: Acts as a versatile substrate for further functionalization, leveraging the difluorobenzoyl moiety.

Basic Information

Product Name	2-(3,4-Difluorobenzoyl)-6-Methylpyridine
CAS No.	1187166-19-3
Molecular Formula	C14H9F2NO
Molecular Weight	245.23 g/mol
Synonyms	6-Methyl-2-(3,4-difluorobenzoyl)pyridine; (3,4-Difluorophenyl)(6-methyl-2-pyridinyl)methanone; 2-(3,4-Difluorobenzoyl)-6-picoline; 2-Pyridinecarboxaldehyde, 6-methyl-, (3,4-difluorophenyl)hydrazone (related); Methanone, (3,4-difluorophenyl)(6-methyl-2-pyridinyl)-; 1187166-19-3
EINECS	Contact for details

Quality Control

Our 2-(3,4-Difluorobenzoyl)-6-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.