Description

2-Chloro-5-(3,4,5-trifluorobenzoyl)pyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in its unique molecular architecture, which combines a halogenated pyridine ring with a polyfluorinated benzoyl group, enabling precise structural modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated aromatic system.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce complex fluorinated motifs.
• Life Science Reagent: Utilized in biochemical research as a probe or labeling compound due to its specific chemical reactivity and potential fluorescence properties.

Basic Information

Product Name	2-Chloro-5-(3,4,5-Trifluorobenzoyl)Pyridine
CAS No.	1187165-43-0
Molecular Formula	C12H5ClF3NO
Molecular Weight	279.62 g/mol
Synonyms	2-Chloro-5-(3,4,5-trifluorobenzoyl)pyridine; 2-Chloro-5-(3,4,5-trifluorobenzoyl)pyridine; 2-Chloro-5-(3,4,5-trifluorobenzoyl)pyridine; 2-Chloro-5-(3,4,5-trifluorobenzoyl)pyridine; 2-Chloro-5-(3,4,5-trifluorobenzoyl)pyridine; 2-Chloro-5-(3,4,5-trifluorobenzoyl)pyridine; 2-Chloro-5-(3,4,5-trifluorobenzoyl)pyridine; 2-Chloro-5-(3,4,5-trifluorobenzoyl)pyridine
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-5-(3,4,5-trifluorobenzoyl)pyridine adheres to stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting compliance in GMP and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.