Description

Ethyl 2-(Methylsulfonyl)Nicotinate is a high-purity organic intermediate featuring a nicotinate core functionalized with a methylsulfonyl group. This compound matters as a critical building block in modern pharmaceutical synthesis, enabling the development of novel active pharmaceutical ingredients (APIs) with targeted properties. It is primarily needed by research and development chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents and herbicides due to its reactive sulfone and ester functionalities.
• Chemical Research & Development: Serves as a versatile precursor for further functionalization (e.g., hydrolysis, amidation, cross-coupling reactions) in academic and industrial labs.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands or organocatalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	Ethyl 2-(Methylsulfonyl)Nicotinate
CAS No.	1186663-29-5
Molecular Formula	C9H11NO4S
Molecular Weight	229.25 g/mol
Synonyms	2-(Methylsulfonyl)nicotinic acid ethyl ester; Ethyl 2-(methylsulfonyl)pyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 2-(methylsulfonyl)-, ethyl ester; Ethyl 2-methanesulfonylnicotinate; 1186663-29-5; Ethyl 2-(methylsulfonyl)nicotinate
EINECS	Contact for details

Quality Control

Our Ethyl 2-(Methylsulfonyl)Nicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.