Description

4-Chloro-3-Iodo-1-(Propan-2-Yl)-1H-Pyrazolo[4,3-C]Pyridine is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. Its unique halogenated pyrazolopyridine core structure makes it a critical intermediate for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). This compound is primarily sought after by research institutions and pharmaceutical companies engaged in drug discovery programs, particularly those focused on kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Development: Acts as a building block for creating novel active ingredients for crop protection products.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Material Science: Potential intermediate for the synthesis of specialty chemicals and advanced organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and development.

Basic Information

Product Name	4-Chloro-3-Iodo-1-(Propan-2-Yl)-1H-Pyrazolo[4,3-C]Pyridine
CAS No.	1186647-71-1
Molecular Formula	C9H7ClIN3
Molecular Weight	319.53 g/mol
Synonyms	1H-Pyrazolo[4,3-c]pyridine, 4-chloro-3-iodo-1-(1-methylethyl)-; 4-Chloro-3-iodo-1-isopropyl-1H-pyrazolo[4,3-c]pyridine; 1-Isopropyl-4-chloro-3-iodo-1H-pyrazolo[4,3-c]pyridine; 1186647-71-1; AI3-63599; AKOS040745176; ZINC000257830789; SCHEMBL21406427
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-3-Iodo-1-(Propan-2-Yl)-1H-Pyrazolo[4,3-C]Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) including purity (HPLC), identity confirmation (NMR, MS), and impurity profile is supplied with each shipment to guarantee reproducible results and supply chain reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and should be handled under inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.