Description

3-Bromo-6-oxo-1,6-dihydropyridine-2-carbonitrile is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it serves as a critical precursor for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. Pharmaceutical researchers, agrochemical developers, and specialty chemical manufacturers need this intermediate for its reactive bromine and nitrile functionalities, which enable key carbon-carbon and carbon-heteroatom bond-forming reactions to create targeted libraries of bioactive compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and antiviral agent discovery.
• Agrochemical Synthesis: Used in the creation of novel herbicides and fungicides, leveraging its heterocyclic core for biological activity.
• Material Science Research: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds or molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up services for clients in the life sciences sector.

Basic Information

Item	Details
Product Name	3-Bromo-6-oxo-1,6-dihydropyridine-2-carbonitrile
CAS No.	1186637-40-0
Molecular Formula	C6H3BrN2O
Molecular Weight	199.01 g/mol
Synonyms	3-Bromo-2-cyano-6-hydroxypyridine; 3-Bromo-6-hydroxy-2-pyridinecarbonitrile; 2-Cyano-3-bromo-6-hydroxypyridine; 3-Bromo-6-oxo-1,6-dihydro-2-pyridinecarbonitrile; 3-Bromo-6-hydroxypicolinonitrile; 1,6-Dihydro-3-bromo-6-oxo-2-pyridinecarbonitrile; 3-Bromo-1,6-dihydro-6-oxo-2-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-oxo-1,6-dihydropyridine-2-carbonitrile is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.