Description

Methyl 6-Chloro-4-Methylpyridine-2-Carboxylate is a high-purity, versatile pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its functionalized structure, which provides a reactive scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Preparation: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and commercial production.

Basic Information

Product Name	Methyl 6-Chloro-4-Methylpyridine-2-Carboxylate
CAS No.	1186605-87-7
Molecular Formula	C8H8ClNO2
Molecular Weight	185.61 g/mol
Synonyms	Methyl 6-chloro-4-methylpicolinate; 2-Pyridinecarboxylic acid, 6-chloro-4-methyl-, methyl ester; 6-Chloro-4-methylpyridine-2-carboxylic acid methyl ester; Methyl 6-chloro-4-methyl-2-pyridinecarboxylate; 6-Chloro-4-methylpicolinic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 6-Chloro-4-Methylpyridine-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.