Description

n-(6-Iodo-2-(Trimethylsilyl)Furo[3,2-B]Pyridin-7-Yl)Pivalamide is a high-value, organosilicon-containing heterocyclic building block designed for advanced synthetic chemistry. This compound matters for its role as a key intermediate in the development of complex pharmaceutical agents and functional materials, offering unique reactivity for constructing intricate molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for lead optimization and the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors or other heterocyclic-based therapeutics.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging its fused furanopyridine core for bioactivity.
• Material Science Precursor: Acts as a specialized monomer or precursor for synthesizing organic electronic materials, such as those used in OLEDs or semiconductors, due to its conjugated system and silicon moiety.
• Chemical Biology Probe Synthesis: Employed to create tagged or modified molecules for studying biological pathways and target engagement, utilizing the iodine atom for further functionalization.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create diverse compound libraries.
• Process Chemistry & Scale-Up: Used in route scouting and optimization for the commercial-scale production of complex target molecules.

Basic Information

Item	Detail
Product Name	n-(6-Iodo-2-(Trimethylsilyl)Furo[3,2-B]Pyridin-7-Yl)Pivalamide
CAS No.	1186310-88-2
Molecular Formula	C15H21IN2O2Si
Molecular Weight	416.34 g/mol
Synonyms	Pivalamide, N-[6-iodo-2-(trimethylsilyl)furo[3,2-b]pyridin-7-yl]-; 7-Pivalamido-6-iodo-2-trimethylsilylfuro[3,2-b]pyridine; 6-Iodo-2-(trimethylsilyl)-7-(pivalamido)furo[3,2-b]pyridine; 1186310-88-2; Furo[3,2-b]pyridine-7-pivalamide derivative
EINECS	Contact for details

Quality Control

Our n-(6-Iodo-2-(Trimethylsilyl)Furo[3,2-B]Pyridin-7-Yl)Pivalamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.