Description

2-((tert-Butyldimethylsilyloxy)Methyl)-Furo[3,2-B]Pyridine-6-Carbonitrile is a high-value, protected heterocyclic building block designed for advanced synthetic chemistry. This compound matters for its role as a key intermediate in the development of complex pharmaceutical molecules, particularly in medicinal chemistry programs targeting novel therapeutic agents. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise chemical to construct intricate molecular architectures, enabling the synthesis of potential drug candidates with specific biological activity.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical development.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug discovery projects.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex fused heterocyclic systems common in bioactive molecules.
• Agrochemical Development: Potential intermediate in the research and synthesis of novel crop protection agents and pesticides.
• Material Science Research: Can be utilized in the development of organic electronic materials and specialty polymers.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.

Basic Information

Item	Detail
Product Name	2-((tert-Butyldimethylsilyloxy)Methyl)-Furo[3,2-B]Pyridine-6-Carbonitrile
CAS No.	1186310-75-7
Molecular Formula	C16H22N2O2Si
Molecular Weight	302.45 g/mol
Synonyms	6-Cyano-2-((tert-butyldimethylsilyloxy)methyl)furo[3,2-b]pyridine; Furo[3,2-b]pyridine-6-carbonitrile, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-; 2-((TBDMS-Oxy)Methyl)-Furo[3,2-B]Pyridine-6-Carbonitrile; TBDMS-protected furopyridine carbonitrile; 2-((tert-Butyldimethylsilyloxy)methyl)furo[3,2-b]pyridine-6-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-((tert-Butyldimethylsilyloxy)Methyl)-Furo[3,2-B]Pyridine-6-Carbonitrile is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) with detailed specifications are provided to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is sensitive to fluoride and strong alkali; ensure it is stored separately from such materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.