Description

Tak-441 is a high-purity, non-peptidic small molecule compound identified by the CAS registry number 1186231-83-3. This compound is valued in advanced research and development for its specific biological activity, serving as a critical tool for investigating novel therapeutic pathways. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on drug discovery and preclinical studies.

Application

• Pharmaceutical Research & Development: Acts as a key reference standard and active pharmaceutical ingredient (API) intermediate in the discovery of new therapeutic agents.
• Biochemical Assay Development: Used as a precise molecular tool to validate assay systems and study specific biological mechanisms of action.
• Preclinical Studies: Employed in in vitro and in vivo models to evaluate pharmacokinetics, pharmacodynamics, and initial efficacy.
• Chemical Biology: Serves as a probe compound for target identification and pathway analysis in complex biological systems.
• High-Throughput Screening (HTS): Utilized as a control or test compound in large-scale screening campaigns to identify new drug candidates.
• Academic Research: Supports fundamental scientific investigations in university and institutional laboratories exploring novel biological targets.

Basic Information

Product Name	Tak-441
CAS No.	1186231-83-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	TAK-441; TAK 441; 1186231-83-3; (S)-N-(1-(7-(4-Fluorophenyl)-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)ethyl)-9H-purin-6-amine; Hedgehog (Hh) Signaling Inhibitor; Hedgehog pathway inhibitor TAK-441; Smoothened (SMO) antagonist.
EINECS	Contact for details

Quality Control

Every batch of Tak-441 is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.