Description

(3-Chloro-5-Trifluoromethyl-Pyridin-2-Yl)-Piperidin-3-Ylmethyl-Amine Hydrochloride, 98+% C12H16Cl2F3N3, Mw: 330.18 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial interest for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective research.
• Agrochemical Research: Serves as a precursor for developing new generation pesticides and herbicides, leveraging the pyridine and trifluoromethyl motifs.
• Chemical Biology Probe Development: Used in the creation of molecular probes for studying enzyme inhibition and receptor binding mechanisms.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization studies for the commercial-scale production of target molecules.
• Custom Synthesis & Contract Manufacturing: Supplied to partners requiring specific, high-purity intermediates for proprietary synthesis projects.

Basic Information

Item	Detail
Product Name	(3-Chloro-5-Trifluoromethyl-Pyridin-2-Yl)-Piperidin-3-Ylmethyl-Amine Hydrochloride
CAS No.	1185319-70-3
Molecular Formula	C12H16Cl2F3N3
Molecular Weight	330.18 g/mol
Synonyms	1-[(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl]piperidin-3-amine hydrochloride; 3-Chloro-5-trifluoromethyl-2-[(3-aminopiperidin-1-yl)methyl]pyridine hydrochloride; 2-[(3-Aminopiperidin-1-yl)methyl]-3-chloro-5-(trifluoromethyl)pyridine hydrochloride; (3-Chloro-5-trifluoromethyl-pyridin-2-yl)-piperidin-3-ylmethyl-amine HCl; CAS 1185319-70-3
EINECS	Contact for details

Quality Control

Our 98+% purity grade is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.