Description

2-[[[3-Methyl-4-(2,2,2-Trifluoroethoxy)-2-Pyridyl]Methyl]Sulfinyl]-5-Methoxy-o- Methyl-1H-Benzimidazole CAS NO 1184993-29-0 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial importance as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of proprietary drug candidates, especially those targeting specific enzyme pathways.
• Active Pharmaceutical Ingredient (API) Development: Used in research and process development for creating new APIs with potential anti-ulcer, anti-cancer, or other specialized therapeutic activities.
• Chemical Research & Development: Employed in academic and industrial R&D labs for structure-activity relationship (SAR) studies and the exploration of new benzimidazole-based compounds.
• Process Chemistry & Scale-Up: A vital material for optimizing synthetic routes and scaling up production from laboratory to pilot and commercial manufacturing scales.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development, validation, and quality control testing in pharmaceutical analysis.

Basic Information

Product Name	2-[[[3-Methyl-4-(2,2,2-Trifluoroethoxy)-2-Pyridyl]Methyl]Sulfinyl]-5-Methoxy-o- Methyl-1H-Benzimidazole
CAS No.	1184993-29-0
Molecular Formula	C18H18F3N3O3S
Molecular Weight	413.41 g/mol
Synonyms	5-Methoxy-2-[[(4-(2,2,2-trifluoroethoxy)-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole; 2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl)sulfinyl)-5-methoxy-1H-benzo[d]imidazole; Benzimidazole derivative CAS 1184993-29-0; Trifluoroethoxy Pyridinyl Methyl Sulfinyl Benzimidazole; TFMPM Benzimidazole Intermediate
EINECS	Contact for details

Quality Control

Our 2-[[[3-Methyl-4-(2,2,2-Trifluoroethoxy)-2-Pyridyl]Methyl]Sulfinyl]-5-Methoxy-o- Methyl-1H-Benzimidazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.