Description

2-Bromo-3-Fluorobenzyl Alcohol is a versatile fluorinated and brominated benzyl alcohol derivative, serving as a critical building block in advanced organic synthesis. Its unique halogen-substituted aromatic structure makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine and bromine atoms can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic cores for electronic materials used in displays and lighting.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Sonogashira couplings to create biaryl structures.
• Ligand & Catalyst Development: Useful for constructing sophisticated chelating ligands in asymmetric catalysis and material science.
• Chemical Research & Development: A standard reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	2-Bromo-3-Fluorobenzyl Alcohol
CAS No.	1184915-45-4
Molecular Formula	C7H6BrFO
Molecular Weight	205.03 g/mol
Synonyms	(2-Bromo-3-fluorophenyl)methanol; 2-Bromo-3-fluorobenzenemethanol; 1-(Bromomethyl)-2-fluoro-3-bromobenzene (incorrect but common misnomer); α-Hydroxymethyl-2-bromo-3-fluorobenzene; 3-Fluoro-2-bromobenzyl alcohol; Benzenemethanol, 2-bromo-3-fluoro-; 2-Bromo-3-fluoro-1-hydroxymethylbenzene
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3-Fluorobenzyl Alcohol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.