Description

1-Cyclohexyl-5-oxopyrrolidine-3-carbonyl chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its core value lies in its versatile carbonyl chloride moiety, which facilitates efficient amide bond formation and other key transformations in complex molecule construction. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of protease inhibitors and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its reactivity to create complex molecular scaffolds.
• Peptidomimetic Research: Serves as a crucial precursor in the design and synthesis of peptidomimetics and constrained peptide analogs.
• Chemical Biology Probes: Employed in the creation of specialized probes and ligands for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.
• Academic & Institutional Research: Used in university and institutional laboratories for methodological development and exploring new chemical spaces.

Basic Information

Product Name	1-Cyclohexyl-5-oxopyrrolidine-3-carbonyl chloride
CAS No.	1181577-49-0
Molecular Formula	C11H16ClNO2
Molecular Weight	229.70 g/mol
Synonyms	1-Cyclohexyl-5-oxopyrrolidine-3-carboxylic acid chloride; 3-(Chlorocarbonyl)-1-cyclohexyl-2-pyrrolidinone; 1-Cyclohexyl-3-(chlorocarbonyl)-2-pyrrolidinone; 2-Pyrrolidinone, 1-cyclohexyl-3-(chlorocarbonyl)-; 5-Oxo-1-cyclohexylpyrrolidine-3-carbonyl chloride; N-Cyclohexyl-5-oxopyrrolidine-3-carbonyl chloride; Cyclohexyl 5-oxopyrrolidine-3-carboxylate chloride (incorrect but common search variant)
EINECS	Contact for details

Quality Control

Our 1-Cyclohexyl-5-oxopyrrolidine-3-carbonyl chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.