Description

2-(2-Fluoro-Phenyl)-2-Methyl-Propan-1-Ol CAS NO 1177192-02-7 is a high-purity fluorinated aromatic alcohol building block, valued for its unique structural motif that combines a tertiary benzylic carbon with a primary alcohol function. This compound is essential for research and development chemists seeking to introduce steric bulk and fluorine atoms into target molecules, which can significantly alter physicochemical properties. It is primarily utilized in the synthesis of advanced pharmaceutical intermediates, agrochemicals, and functional materials where precise molecular architecture is critical.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in constructing advanced herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts in asymmetric synthesis.
• Material Science Research: Employed in the creation of specialty polymers and liquid crystals, leveraging the fluorine group to modify surface energy and optical properties.
• Chemical Biology Probes: Useful for synthesizing fluorinated probes and tags for imaging and diagnostic applications.

Basic Information

Product Name	2-(2-Fluoro-Phenyl)-2-Methyl-Propan-1-Ol
CAS No.	1177192-02-7
Molecular Formula	C10H13FO
Molecular Weight	168.21 g/mol
Synonyms	2-(2-Fluorophenyl)-2-methylpropan-1-ol; 1-(2-Fluorophenyl)-2-methyl-2-propanol; α,α-Dimethyl-2-fluorobenzyl alcohol; 2-Fluoro-α,α-dimethylbenzyl alcohol; (2-Fluorophenyl)dimethylmethanol; 2-Methyl-2-(2-fluorophenyl)propan-1-ol; 2-Fluoro-α,α-dimethylbenzenemethanol
EINECS	Contact for details

Quality Control

Our 2-(2-Fluoro-Phenyl)-2-Methyl-Propan-1-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications in cGMP environments and research requiring the highest material integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.