Description

1-Benzyl-1H-Pyrazole-4-Carbonyl Chloride is a versatile and highly reactive organic building block, specifically an acyl chloride derivative of a benzyl-protected pyrazole. This compound is crucial for the efficient synthesis of amides and esters, serving as a key intermediate in advanced organic and medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for creating amide bonds in target molecules.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the creation of specialized polymers, ligands, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling proteins or modifying biomolecules in probe development.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and complex intermediates.
• Academic Research: Utilized in university and institutional labs for methodological development and exploratory synthesis.

Basic Information

Product Name	1-Benzyl-1H-Pyrazole-4-Carbonyl Chloride
CAS No.	1174665-95-2
Molecular Formula	C11H9ClN2O
Molecular Weight	220.66 g/mol
Synonyms	1-Benzyl-1H-pyrazole-4-carbonyl chloride; 1-Benzylpyrazole-4-carbonyl chloride; 4-(Chlorocarbonyl)-1-benzyl-1H-pyrazole; 1-Benzyl-4-(chlorocarbonyl)-1H-pyrazole; 1H-Pyrazole-4-carbonyl chloride, 1-benzyl-; 1174665-95-2
EINECS	Contact for details

Quality Control

Our 1-Benzyl-1H-Pyrazole-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Solubility	Soluble in common organic solvents (DCM, THF, DMF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.