Description

5-Cyanopicolinoyl Chloride is a high-purity, reactive chemical intermediate essential for constructing complex heterocyclic scaffolds. Its value lies in its bifunctional nature, combining a reactive acid chloride group with a versatile nitrile moiety, enabling efficient synthesis of advanced pharmaceutical and agrochemical compounds. This product is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides requiring pyridine-based structures.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, metal-organic frameworks (MOFs), and functional polymers.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	5-Cyanopicolinoyl Chloride
CAS No.	1173834-29-1
Molecular Formula	C7H3ClN2O
Molecular Weight	166.56 g/mol
Synonyms	5-Cyanopyridine-2-carbonyl chloride; 2-Pyridinecarbonyl chloride, 5-cyano-; 5-Cyano-2-pyridinecarboxylic acid chloride; 5-Cyanopicolinic acid chloride; 5-CN-Pic-Cl; 5-Cyanopyridine-2-carboxylic acid chloride; 2-Carbonyl chloride-5-cyanopyridine
EINECS	Contact for details

Quality Control

Every batch of 5-Cyanopicolinoyl Chloride is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as assay (HPLC), identity (IR, NMR), and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and maintain stability. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.