Description

(2E)-3-(1-Ethyl-3,5-Dimethyl-1H-Pyrazol-4-Yl)Acryloyl Chloride is a high-value, reactive acyl chloride intermediate essential for advanced organic synthesis. Its core value lies in enabling the efficient introduction of a functionalized acryloyl moiety, facilitating the development of novel compounds with tailored properties. This product is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the pyrazole-acryloyl scaffold imparts specific biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent precursor for developing functional polymers with specialized optical or electronic properties.
• Chemical Biology Probes: Employed in the creation of activity-based probes and affinity labels for studying enzyme function and protein interactions.
• Ligand & Catalyst Development: Facilitates the synthesis of novel chelating ligands and organometallic complexes for catalytic applications.

Basic Information

Product Name	(2E)-3-(1-Ethyl-3,5-Dimethyl-1H-Pyrazol-4-Yl)Acryloyl Chloride
CAS No.	1173598-22-5
Molecular Formula	C10H13ClN2O
Molecular Weight	212.68 g/mol
Synonyms	(E)-3-(1-Ethyl-3,5-dimethyl-1H-pyrazol-4-yl)acryloyl chloride; 1-Ethyl-3,5-dimethyl-4-[(1E)-3-chloro-3-oxo-1-propen-1-yl]-1H-pyrazole; trans-3-(1-Ethyl-3,5-dimethyl-1H-pyrazol-4-yl)acryloyl chloride; 3-(1-Ethyl-3,5-dimethylpyrazol-4-yl)propenoyl chloride; (E)-3-(1-Ethyl-3,5-dimethyl-1H-pyrazol-4-yl)prop-2-enoyl chloride; Pyrazole acryloyl chloride derivative; 1173598-22-5
EINECS	Contact for details

Quality Control

Our production of (2E)-3-(1-Ethyl-3,5-Dimethyl-1H-Pyrazol-4-Yl)Acryloyl Chloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and IR spectroscopy. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated) for optimal stability. Due to its nature as a strong acid/organic solvent, it should be kept away from moisture, strong bases, and oxidizing agents. Handle and store under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	Light yellow to amber liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.