Description

2-Fluorobenzyl Thiocyanate is a versatile fluorinated organic building block containing both a thiocyanate (-SCN) and a benzyl group. This compound is valued for its dual functional groups, which enable its use as a key intermediate in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working in medicinal chemistry, material science, and fine chemical synthesis. The specific reactivity of the thiocyanate group makes it a valuable precursor for heterocycle formation and ligand development.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers or organic electronic materials where fluorine incorporation modifies physical properties.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags due to the reactive thiocyanate moiety, which can conjugate with biomolecules.
• Fine Chemical Manufacturing: Acts as a building block for various specialty chemicals used in flavors, fragrances, and advanced organic synthesis.

Basic Information

Item	Detail
Product Name	2-Fluorobenzyl Thiocyanate
CAS No.	1173440-93-1
Molecular Formula	C8H6FNS
Molecular Weight	167.20 g/mol
Synonyms	1-(Fluoromethyl)-2-thiocyanatobenzene; (2-Fluorophenyl)methyl thiocyanate; α-Fluoro-o-tolyl thiocyanate; 2-Fluorobenzylthio cyanate; o-Fluorobenzyl thiocyanate; 2-Fluorobenzyl isothiocyanate (common misnomer); 2-Fluoro-benzenemethanethiol, cyanate
EINECS	Contact for details

Quality Control

Our 2-Fluorobenzyl Thiocyanate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and consistent performance. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We adhere to cGMP guidelines for the production of materials intended for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.