Description

4-Chloro-1-Ethyl-1H-Pyrazole-3-Carbonyl Chloride is a versatile and highly reactive bifunctional organic intermediate, serving as a critical building block in advanced chemical synthesis. Its value lies in the dual reactivity of the acid chloride and chloro-substituted pyrazole moieties, enabling efficient construction of complex heterocyclic scaffolds. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Used in the creation of specialty polymers, ligands for catalysis, and advanced organic electronic materials.
• Chemical Research: A valuable reagent in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Peptide Mimetics: Facilitates the incorporation of heterocyclic motifs into peptide backbones to modulate biological activity and stability.

Basic Information

Product Name	4-Chloro-1-Ethyl-1H-Pyrazole-3-Carbonyl Chloride
CAS No.	1172515-44-4
Molecular Formula	C6H6Cl2N2O
Molecular Weight	193.03 g/mol
Synonyms	1-Ethyl-4-chloro-1H-pyrazole-3-carbonyl chloride; 4-Chloro-1-ethylpyrazole-3-carbonyl chloride; 1H-Pyrazole-3-carbonyl chloride, 4-chloro-1-ethyl-; 1172515-44-4; 4-Chloro-1-ethyl-1H-pyrazole-3-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-1-Ethyl-1H-Pyrazole-3-Carbonyl Chloride adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) and separated from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.