Description

3-Methyl-6-(Trimethylsilyl)-3H-Imidazo[4,5-B]Pyridine is a high-value, organosilicon-functionalized heterocyclic compound, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both an imidazopyridine core and a trimethylsilyl protecting group, makes it indispensable for constructing complex molecules with precise electronic and steric properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science: Serves as a precursor for organic semiconductors, ligands for catalysis, and other functional organic materials.
• Chemical Synthesis: Acts as a versatile intermediate in organic synthesis, where the trimethylsilyl group can be used for protection or further functionalization.
• Academic & R&D: Employed in university and industrial research laboratories for methodological studies and the exploration of new chemical spaces.

Basic Information

Product Name	3-Methyl-6-(Trimethylsilyl)-3H-Imidazo[4,5-B]Pyridine
CAS No.	1171920-66-3
Molecular Formula	C12H19N3Si
Molecular Weight	233.39 g/mol
Synonyms	3-Methyl-6-(trimethylsilyl)-3H-imidazo[4,5-b]pyridine; 3H-Imidazo[4,5-b]pyridine, 3-methyl-6-(trimethylsilyl)-; 6-(Trimethylsilyl)-3-methyl-3H-imidazo[4,5-b]pyridine; 3-Methyl-6-trimethylsilyl-3H-imidazo[4,5-b]pyridine; CAS 1171920-66-3; TMS-imidazopyridine derivative; Silylated imidazopyridine intermediate
EINECS	Contact for details

Quality Control

Every batch of 3-Methyl-6-(Trimethylsilyl)-3H-Imidazo[4,5-B]Pyridine is produced and analyzed under strict quality management protocols to ensure high purity and batch-to-batch consistency. Our standard grade typically meets a purity specification of ≥95% (by HPLC), suitable for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We can support custom synthesis to meet specific purity requirements (e.g., ≥98% or ≥99%) for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.