Description

2-((tert-Butyldimethylsilyloxy)Methyl)-6-(Trimethylsilyl)Furo[3,2-B]Pyridine is a high-value, organosilicon-protected heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for researchers and process chemists requiring precise control over molecular architecture in complex multi-step syntheses. Its primary utility lies in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its unique fused-ring structure for biological activity.
• Material Science Precursor: Serves as a specialized monomer or precursor for advanced organic electronic materials and functional polymers.
• Academic & R&D Synthesis: An essential reagent for methodological development and total synthesis of natural products in university and institutional research laboratories.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of fine chemicals and active pharmaceutical ingredients (APIs).

Basic Information

Product Name	2-((tert-Butyldimethylsilyloxy)Methyl)-6-(Trimethylsilyl)Furo[3,2-B]Pyridine
CAS No.	1171920-41-4
Molecular Formula	C18H31NO2Si2
Molecular Weight	349.62 g/mol
Synonyms	6-(Trimethylsilyl)-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]furo[3,2-b]pyridine; 2-((TBDMSO)Methyl)-6-(TMS)Furo[3,2-B]Pyridine; 2-(((tert-Butyldimethylsilyl)oxy)methyl)-6-(trimethylsilyl)furo[3,2-b]pyridine; Furo[3,2-b]pyridine, 2-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-6-(trimethylsilyl)-; TBDMS-protected furopyridine derivative; Silyl-protected furopyridine intermediate
EINECS	Contact for details

Quality Control

Our production of 2-((tert-Butyldimethylsilyloxy)Methyl)-6-(Trimethylsilyl)Furo[3,2-B]Pyridine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.