Description

6-((tert-Butyldimethylsilyloxy)Methyl)-Furo[3,2-B]Pyridine is a high-purity, advanced pharmaceutical intermediate featuring a protected hydroxymethyl group on a fused furopyridine scaffold. This compound matters as a critical building block in the synthesis of complex bioactive molecules, offering precise control over molecular architecture for drug discovery programs. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the research and development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the development of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors or other small-molecule therapeutics.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Process Chemistry: Serves as a standardized building block for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions.
• Chemical Biology: Can be utilized as a probe or linker in the synthesis of chemical tools for target identification and validation.
• Academic Research: Employed in university and institutional labs for methodological development in heterocyclic and organosilicon chemistry.

Basic Information

Product Name	6-((tert-Butyldimethylsilyloxy)Methyl)-Furo[3,2-B]Pyridine
CAS No.	1171920-21-0
Molecular Formula	C15H23NO2Si
Molecular Weight	277.44 g/mol
Synonyms	6-((tert-Butyldimethylsilyloxy)methyl)furo[3,2-b]pyridine; 6-(((tert-Butyldimethylsilyl)oxy)methyl)furo[3,2-b]pyridine; TBDMS-protected 6-(hydroxymethyl)furo[3,2-b]pyridine; 6-((Tert-butyldimethylsilyloxy)methyl)furo[3,2-b]pyridine; Furo[3,2-b]pyridine, 6-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-; 6-((TBDMSO)Methyl)-Furo[3,2-B]Pyridine
EINECS	Contact for details

Quality Control

Our 6-((tert-Butyldimethylsilyloxy)Methyl)-Furo[3,2-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full batch traceability are provided to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.